Interaction Checker

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Ten classic chemotherapy drugs have been added to the interaction checker

Tuesday 24 September 2019

5-fluorouracil, cabazitaxel, docetaxel, doxorubicin (liposomal), epirubicin, gemcitabine, irinotecan, methotrexate, paclitaxel and vinorelbine are now listed in the interaction checker as cancer drugs and interactions can be found with all the comedications.

  • 5-fluorouracil (Fluorouracil®, Efidix®, Efudex®) is an antimetabolite and is indicated for the treatment of basal-cell carcinoma, breast cancer, colon cancer, colorectal cancer, gastric cancer, head and neck cancer, malignant skin lesions, oesophageal cancer, pancreatic cancer and rectal cancer.

  • Cabazitaxel (Jevtana®) is a microtubule inhibitor and is indicated for the treatment of prostate cancer.

  • Docetaxel (Taxotere®) is a microtubule inhibitor and is indicated for the treatment of breast cancer, gastric adenocarcinoma, head and neck cancer, non-small cell lung cancer and prostate cancer.

  • Doxorubicin liposomal (Caelyx®, Doxil®, Doxorubicin®, Myocet®) is an anthracycline antibiotic and is indicated for the treatment of AIDS-related Kaposi’s sarcoma, breast cancer, multiple myeloma and ovarian cancer.

  • Epirubicin (Pharmorubicin®, Ellence®) is an anthracycline antibiotic and is indicated for the treatment of bladder cancer, breast cancer, colorectal cancer, gastric cancer, leukaemia, lymphoma, ovarian cancer and small cell lung cancer.

  • Gemcitabine (Gemzar®, Infugem®) is an antimetabolite and is indicated for the treatment of bladder cancer, breast cancer, non-small cell lung cancer, ovarian cancer and pancreatic cancer.

  • Irinotecan (Campto®, Camtosar®, Onivyde®) is a topoisomerase I inhibitor and is indicated for the treatment of colon cancer, colorectal cancer, pancreatic cancer and rectal cancer.

  • Methotrexate (Jylamvo®, Matrex®, Methotrexate®, Xatmep®) is an antimetabolite and is indicated for the treatment of acute lymphoblastic leukaemia, bladder cancer, breast cancer, cervical cancer, choriocarcinoma, cutaneous T-cell lymphoma, head and neck cancer, lung cancer, meningeal leukaemia, Non-Hodgkin’s lymphoma, osteogenic sarcoma, ovarian cancer and soft-tissue sarcoma.

  • Paclitaxel (Abraxane®, Paclitaxel®, Taxol®) is a microtubule inhibitor and is indicated for the treatment of AIDS-related Kaposi’s sarcoma, breast cancer, non-small cell lung cancer, ovarian cancer and pancreatic cancer.

  • Vinorelbine (Navelbine®, Vinorelbine®) is a vinca alkaloid and is indicated for the treatment of breast cancer and non-small cell lung cancer.
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